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| Advances in Controlled Delivery of Drugs | |||||||
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| Ultrasonically Medicated Drug Delivery Implantable Drug Delivery Polyethylene-Starch Extrudates as Erodible Carriers for Bioactive Materials: I Erodibility and in vitro Dye Release Studies Bioactive Polymers: In vitro and in vivo Study of Controlled Release Neomycin Polymer Entrapment Powders for Topical Delivery Bioactive Polymers 68-Controlled Release of Neomycine-Furazolidone Bicomponent System from Xanthan Hydrogel Effect of Controlled Local Acetylsalicylic Acid Release on in vitro Platelet Adhesion to Vascular Grafts Materials Used in Controlled Release Technology-A Primer | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 1566761948 | PGS: 154 | List: 199.95 YOUR PRICE: 189.95 | |||
| Alcohol and Drug Abuse as Encountered in Office Practice | |||||||
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| BACKGROUND. Introduction to Abused Substances. Terminology, Definitions, FDA Classifications, DSM III R Diagnostic Criteria. Molecular Basis of Action of Abused Substances. Etiology of Substance Abuse; Similarities of Alcohol and Drug Abuse. Essential Pharmacology of Abused Drugs. Issues of Law and Custom. Attitudes Among Medical Staff Influencing Substance Abuse Care. SKILLS. Obtaining an Accurate Drug and Alcohol History. Recognition of the Alcoholic and Substance-Abusing Patient in Your Practice. Emergencies in Drug and Alcohol Use and Their Management. Laboratory Use in Screening and Verification of Drug Use. Cost-Effective Screening of Addicted Persons for Significant Illness. Classes of Drugs Needed for the Successful Management of Addiction. Informing the Patient of the Diagnosis of Abuse and Motivating Him to Treatment. SUBSTANCES AND THEIR SPECIFIC PROBLEMS. What Can Be Learned from Smoking and Nicotine Addiction. Alcohol and Sedatives. Medical Problems in Alcoholics. Psychiatric Problems in Addicts. Opium Derivatives. Medical Problems Related to illicit Drugs. Cocaine and Amphetamines. Marijuana. Hallucinogens and Phencyclidine. Miscellaneous Abused Drugs. Mixed Drug Abuse. TREATMENT AND REHABILITATION. What Is Treatment and What Does It Accomplish? Drug Withdrawal: Recognition and Treatment. Entering Treatment. Professionals and Others Providing Skilled Services to Substance Abusers. The Range of Treatment and Rehabilitation Programs: Factors in the Selection of an Appropriate Program. Setting and Meeting Realistic Goals for Rehabilitation. Volunteer Groups in the Treatment of Addictions: The Model of Alcoholics Anonymous. Crises in Treatment. Prevention and Pertinent Public Health Issues. SPECIAL GROUPS. Special Problems of Substance Abuse in Adolescence. Special Problems in Women Abusers. Problems of Addiction During Pregnancy and Problems in the Child. Children of Alcoholics and Drug Abusers. Alcoholism and Addictions in the Elderly. Addictions in Ethnic and Special Social Groups. Abuse in Professionals. Glossary. | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0849301661 | PGS: 336 | List: 229.95 YOUR PRICE: 218.45 | |||
| Allelopathy: Chemistry and Mode of Action of Allelochemicals | |||||||
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| Introduction Reality and Future of Allelopathy, G.R. Waller Chemistry Studies Ecophysiology and Potential Modes of Action for Selected Lichen Secondary Metabolites, J. Romagni, R.C. Rosell, N.P.D. Nanayakkara, and F.E. Dayan Bioactive Compounds from Potomagetonaceae on Aquatic Organisms, M. della Greca, A. Fiorentino, and M. Isidori Fate of Phenolic Allelochemicals in Soils: the Role of Soil and Rhizosphere Microorganisms, U. Blum Benzoxazolin-2(3H)-ones: Generation, Effects, and Detoxification in the Competition Among Plants, D. Sicker, H. Hao, and M. Schulz Heliannanes: A Structure-Activity Relationship (SAR) Study, F.A. Macías, J. C. G. Galindo, and J.M.G. Molinillo Chemistry of the Host-Parasite Interactions, J.C.G. Galindo, F.A. Macías, M.D. Díaz, and J. Jorrín Application of Analytical Techniques to the Determination of Allelopathic Agents in Wheat Root Exudates: A Practical Case Study, T. Haig The Importance of Alkaloidal Functions, M.S. Blum Allelochemical Properties of Quinolizidine Alkaloids, M. Wink Mode of Action Studies Mode of Action of Phytotoxic Terpenoids, S.O. Duke and A. Oliva Mode of Allelochemical Actions of Phenolic Compounds, F. Einhellig Mode of Action of Hydroxamic Acid BOA and Other Related Compounds, A.M. Sánchez-Moreiras, T. Coba de la Peña, A. Martínez, L. González, F. Pellisier, and M.J. Reigosa Mode of Action of Phytotoxic Fungal Metabolites, H.G. Cutler, S.J. Cutler, and D. Matesic Proteomic Techniques for the Study of Allelopathic Stress Produced by Some Mexican Plants on Protein Patterns of Bean and Tomato, R. Cruz-Ortega, T. Romero-Romero, G. Ayala-Cordero, and A.L. Anaya Application of Microscopic Techniques of the Study of Seeds and Microalgae Under Olive Oil Wastewater Stress, G. Alliota, R. Ligrone, C. Ciniglia, A. Pollio, M. Stanzione, and G. Pinto Bioassays: Valuable Tools for the Study of Allelopathy, R. Hoagland and R.D. Williams | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0849319641 | PGS: 392 | List: 189.95 YOUR PRICE: 180.45 | |||
| Antibiotic Development and Resistance | |||||||
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| Part 1. The Clinical Context. Part 2. Mechanisms of Antibiotic Resistance. Part 3. Bacterial Genetics and Antibiotic Resistance Dissemination. Part 4. Reversibility of Antibiotic Resistance. Part 5. Development of New Antibiotics. | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0415272173 | PGS: N/A | List: 199.95 YOUR PRICE: 189.95 | |||
| AnticoagulantsPhysiologic, Pathologic, and Pharmacologic | |||||||
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| Physiologic Inhibitors: Clinical and Physiological Manifestations of the Protein C Anticoagulant Pathway (C.T. Esmon). Protein S: Clinical and Laboratory Aspects (P.C. Comp). Antithrombin III (M. Manco-Johnson). Tissue Factor Pathway Inhibitor-A Regulator of Tissue Factor Induced Coagulation (M.S. Bajaj, A. Ameri, and S.P. Bajaj). Pathologic Inhibitors: Overview of Factor VIII Inhibitors (J.A. Penner). Immune Tolerance: Historical Perspective and Future Direction (D.M. DiMichele). Inhibitors of Factor VIII in Non-Hemophiliacs (D. Green). The Treatment of Acquired Hemophilia with Porcine Factor VIII Concentrate (C.M. Kessler). Use of Factor IX Complex Concentrates (Prothrombin Complex Concentrates) in Hemophiliacs with Inhibitor Antibodies to Factor VIII or Factor IX (J.M. Lusher). Pathologic Inhibitors (S. Glazer, U. Hedner, J.F. Falch). Lupus Anticoagulants (J.R. Chediak). Acquired von Willebrand's Disease (G.A. Soff). Acquired Inhibitors of Fibrin Stabilization: A Class of Hemorrhagic Disorders of Diverse Origins (L. Lorand). Pharmacologic Inhibitors: Heparin Therapy: Recent Advances in the Treatment of Venous and Arterial Thrombosis (G.F. Pineo, G.E. Raskob, and R.D. Hull). Warfarin Therapy (G.E. Raskob, P.C. Comp, G.F. Pineo, and R.D. Hull). Low Molecular Weight Heparins in the Management of Thrombotic Disorders (J. Fareed, D. Hoppensteadt, J.M. Walenga, W. Jeske, and A. Ahsan). Thrombolytic Therapy-Old and New (H.C. Kwaan). | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0849347629 | PGS: 288 | List: 359.95 YOUR PRICE: 341.95 | |||
| Antigen Processing and Recognition | |||||||
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| The Biology of Antigen Processing and Presentation (James McCluskey, Rozanne Blok, Andrew Brooks, Weisan Chen, Dawn Kanost, and Lars Kjer-Nielsen). Structure and Function of Major Histocompatibility Complex Molecules (Russel D. Salter). Nature and Specificity of Human Class II Molecule Interactions with Peptide Antigens (Alessandro Sette, Deirdre O'Sullivan, and Howard Grey). Antigen Processing and Presentation by Class I MHC (Andrew J. McMichael, Brigitte A. Askonas, and Jeffrey A. Frelinger). Structural Correlates of MHC Class I Restricted Antigen Specific and Alloreactive Immunity (Sebastian Joyce, Thomas P.J. Garrett, Jan Geliebter, Rui Sun, and Stanley G. Nathenson). The Use of Soluble Proteins to Study Class I-Restricted Processing, Presentation, and T Cell Development (Francis R. Carbone). The Nature of the Ligand Recognized by Alloreactive T Cells (Robert Lechler and Giovanna Lombardi). Is Allorecognition Really Anomalous? (David D. Eckels). The Definition and Expression of Minor Histocompatibility Antigens (Bruce E. Loveland and Kirsten Fischer Lindahl). Bacterial Superantigens (Karin J. Purdie, Keith Hudson and John D. Fraser). Molecular Analysis of the Class II Associated Invariant Chain (Norbert Koch, Ulrich Pessara, Klaus Schenck, and Christopher Wraight). Contribution of Accessory Molecules to MHC/Antigen Presentation: Role of CD2/LFA-3 Interactions in T Cell Recognition of Nominal Antigens (Shigeo Koyasu and Ellis L. Reinherz | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0849369320 | PGS: 272 | List: 420.00 YOUR PRICE: 399.00 | |||
| Antimicrobial Therapy in Abdominal Surgery: Precepts and Practices | |||||||
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| Over the past 50 years, important developments have taken place in surgical and antimicrobial aspects of the management of intestinal surgery and intra-abdominal sepsis. Many new pathogens like Clostridium difficile, Helibacter and Ruminococcus have been described, and many new beta-lactam drugs and quinolones have been introduced. Immunological aspects such as T cell factors and interleukins have been shown to play an important role in the pathogenesis of intra-abdominal sepsis. Important new pieces of surgical hardware, sutures, and surgical glues to salvage solid organs were added to the surgical armanentorium. This new book looks at all of these important developments and more. Over 900 articles were reviewed to synthesize the core information for this book. The editors' years of experience in trauma surgery and intra-abdominal sepsis add to the tremendous amount of information found in this book written for physicians, house-staff, and medical students. | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0849342694 | PGS: 120 | List: 229.95 YOUR PRICE: 218.45 | |||
| Antimicrobial/Anti-Infective Materials: Principles and Applications | |||||||
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| PERSPECTIVES ON INFECTIOUS DISEASE CHALLENGES AND ANTIMICROBIAL ANSWERS Antimicrobials Mode of Action and Interaction Host-Parasite Relationship Infectious Disease Challenges Foodborne Diseases and Related Issues Antimicrobial Drug Resistance and Related Issues Rational Use of Antimicrobials Device-Related Infections INFECTIONS OF INTRACARDIAC DEVICES Cardiac Pacemakers Implantable Cardioverter Defibrillators Left Ventricular Assist Devices Prosthetic Cardiac Valves INFECTIONS IN ORTHOPAEDICS Osteomyelitis: Definition, Classification, and Relationship to Orthopaedic Devices Etiology and Establishment of Infections on Orthopaedic Devices Conventional Diagnostic and Treatment Regimens for Osteomyelitis Alternative Approaches to Infection Treatment and Prophylaxis Implant Surfaces That Are Passive and/or Anti-Adhesive Regulatory Issues PHYSIOCHEMICAL BASIS OF BACTERIAL ADHESION TO BIOMATERIAL SURFACES Bacterial Adhesion as a Dynamic Process Properties and Structure of Bacterial Cell Surfaces Non-Specific Adhesion Mechanisms Specific Adhesion Mechanisms Other Factors Affecting Adhesion ALBUMIN AFFINITY COATINGS MAY PREVENT FOREIGN-BODY INFECTIONS Foreign-Body Infections Protein Adsorption Blood Coagulation Fibronolysis Platelet Adhesion Microbial Adhesion Medical-Device Coatings IMMOBILIZED BIOCIDES AS AN ALTERNATIVE STRATEGY FOR CONTROL OF MICROBIAL CONTAMINATION Synthesis of the Immobilized Peptide Systems Biological Activity Chemical and Physical Stability Discussion and Implications ANTI-INFECTIVE COATINGS REDUCE DEVICE-RELATED INFECTIONS Biology on the Surfaces of Indwelling Devices Anti-Infective Medical Devices by Surface Treatment o Further Research REDUCED IMPLANT-RELATED INFECTIOUS COMPLICATIONS BY SURFACE MODIFICATION PROVIDING CONTROLLED ANTIMICROBIAL RELEASE Surface Modification for Controlled Gentamicin Release Animal Studies-Safety and Efficacy Testing A CHEMICALLY INTELLIGENT INFECTION-RESISTANT COATING Anti-Infective Coating Exhibiting Chemical Intelligence Mechanism of Action Coating Stability Bacterial Grow Through Resistance in Coated Microporous Membranes Efficacy Against Biofilms MERGING OF BIOMEDICAL AND TEXTILE TECHNOLOGIES IN ORDER TO CREATE INFECTION-RESISTANT PROSTHETIC VASCULAR GRAFTS Infection of Prosthetic Vascular Grafts Efforts to Combat Graft Infection Textile Dyes Versus Antibiotics: Structural and Chemical Similarities Fluoroquinolone Antibiotics Interaction of Fibers and Small Molecules Application of Fluoroquinolones to Polyester via Pad/Heat Dyeing ASEPTIC APPROACHES AND NOVEL ANTIMICROBIAL CATHETERS FOR PREVENTION OF INFECTION OF VASCULAR CATHETERS Aseptic Approaches Novel Anti-Infective Catheters ANTI-INFECTIVE DEVICES IN OTOLARYNGOLOGY: CURRENT APPLICATIONS AND FUTURE OPPORTUNITIES Otology: Trans-Tympanic Ventilation Tubes Present Examples of Anti-Infective Ventilation Tubes Laryngology: Airway Management Devices and Voice Protheses Rhinology: Nasal Packing, Sinus Stents, and Nasal Septal Buttons LABORATORY METHODS FOR ANTIMICROBIAL SUSCEPTIBILITY TESTING: INDICATIONS FOR SUSCEPTIBILITY TESTING Susceptibility Test Methods Special Susceptibility Tests Selection and Reporting of Antimicrobial Agents Emerging Resistance Problems TOWARD DOLLAR DEVICES FOR MEASURING METABOLIC BIOCHEMISTRY A "Simpler" Approach to Bioluminescence-Based Analysis The ATP Platform Substrate Specific Sensors Multi-Analyte Panels Samples Other Technologies SISYPHUS IN THE MICROBIAL WORLD: ANTIMICROBIAL STRATEGIES AND HUMANITY'S HEALTH Role of Science and Technology in Epidemiological Shifts in Human History Multidimensional Antimicrobial Strategies: Coping with the Global Threat of Antimicrobial Resistance Antimicrobial Strategies Through the Lens of the Law Science, Antimicrobial Strategies, and Future Plagues Index | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 1566767946 | PGS: 346 | List: 269.95 YOUR PRICE: 256.45 | |||
| Antioxidants and Disease Prevention | |||||||
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| Introduction, H.S. Garewal The Safety of Beta-Carotene and the Antioxidant Vitamins C and E, A.T. Diplock Antioxidants and Immune Function, P.F. Inserra, S.K. Ardestani, and R.R. Watson Antioxidants and AIDS, Z. Ahang, P.F. Inserra, and R.R. Watson Antioxidants and Cancer: The Epidemiologic Evidence, J.W. McLarty Antioxidants and Lung Cancer, S.T. Mayne and R.G. Zeigler Antioxidant Nutrients and Oral Cavity Cancer, H.S. Garewal Selenium and Cancer Prevention, G.F. Combs, Jr. and L. Clark Antioxidants and LDL Oxidation, C.J. Fuller and I. Jialal Antioxidants and Coronary Artery Disease Prevention, R.M. Hoffman and H.S. Garewal Nutritional Antioxidants and Prevention of Age-Related Eye Disease, P.F. Jacques Index | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0849385091 | PGS: 208 | List: 229.95 YOUR PRICE: 218.45 | |||
| Antisense Research and Applications | |||||||
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| Introduction. Nucleic Acid Structure and Function. Antisense RNA. Medicinal Chemistry of Oligonucleotides. First Generation Analogs. Newer Analogs. Mechanisms of Action of Current Synthetic Oligonucleotides. Pharmacokinetics and Toxicology. Activities of Current Antisense Drugs. Index. | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 084934705X | PGS: 624 | List: 462.00 YOUR PRICE: 438.90 | |||
| Antithrombotic Drugs in Thrombosis Models | |||||||
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| Introduction. The Rational Basis of Thrombosis Models. Basic Methods. Effects of Antithrombotics and Results of Drug Screening. Drug Combinations. General Conclusions. | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0849351626 | PGS: 240 | List: 379.95 YOUR PRICE: 360.95 | |||
| APPLIED PHARMACOKINETICS | |||||||
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| APPLIED THERAPEUTICS INC | ISBN: 0915486156 | PGS: N/A | List: 91.00 YOUR PRICE: 91.00 | ||||
| Aseptic Pharmaceutical Manufacturing II: Applications for the 1990s | |||||||
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| Chapters include: Controlled Environments in the Pharmaceutical & Medical Products Industry: A Global View, R. Dabbah Quality Systems & Total Quality, K. Stephens Aseptic Processing of Healthcare Products, M. Korczynski & J. Lyda Validation of Aseptic Processes, V. Kumar & R. Murty Laboratory Techniques, R. Mehta & R. Murty Aseptic Production: Radiopharmaceuticals, P. Bremer Education & Training of Personnel, M. Akers Predictive Sterility Assurance for Aseptic Processing, C. Sinclair & A. Tallentire Aseptic Processing of Biopharmaceuticals, N. Lugo Lyophilization, E. Trappler Lyophilization Under Barrier Technology, J. Snowman Aseptic Packaging and Labeling, R. Murty Barrier Isolation Technology: A Systems Approach, J. Lysfjord, P. Haas, H. Melgaard & I. Pflug Hydrogen Peroxide Vapor Sterilization: Applications in the Production Environment, L. Edwards & R. Childers Appendix: USP 23 Chapter 1116: Microbiological Evaluation of Clean Rooms and Other Controlled Environments, United States Pharmacopoeial Convention, Inc. | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0935184775 | PGS: 540 | List: 289.95 YOUR PRICE: 275.45 | |||
| Autonomic Pharmacology | |||||||
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| Section 1: Introduction. Anatomy and Physiology of the Autonomic Nervous System. Section 2: Sympathetic NORADRENERGIC Neurones. Sympathetic Neurotransmission. Drugs Affecting Noradrenergic Neurones. Sympathomimetic Amines. Alpha- and Bet-Adrenoceptor Antagonists. Section 3: Cholinergic Neurotransmission. Parasympathomimetic Amines. Muscarine Receptor Antagonists. Anticholinesterases. Drugs Affecting Autonomic Ganglia. Section 4: Non-Adrenergic Non-Cholinergic NANC Neurones. History and Evidence for NANC Neurones. Putative NANC Transmitters. Section 5: Subcellular Mechanisms of Autonomic Receptor Mediated Effects. Alpha-Adrenoceptors and Muscarine Receptors. Beta-Adrenoceptors. Section 6: Experimental Methodology. In Vivo Methods and Models. In Vitro Methods. Receptor Binding Methods. | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0748405569 | PGS: N/A | List: 359.95 YOUR PRICE: 341.95 | |||
| Basic Occupational Medicine: A Guide to Developing Delivery Systems | |||||||
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| Preface. Introduction. Initial Visit. Follow-Up. Examinations. Critiques. Working with the Physician's Assistant. Working with the In-Plant Occupational Health Nurse. Working with the Consultant: Relationships with the Medical Community. Start-Up and Operation of an Industrial Clinic or Department. Appendix. FEATURES: | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0849342902 | PGS: 192 | List: 229.95 YOUR PRICE: 218.45 | |||
| BEDSIDE CLINICAL PHARMACOKINETICS: SIMPLE TECHNIQUES FOR INDIVIDUALIZING DRUG THERAPY | |||||||
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| APPLIED THERAPEUTICS INC | ISBN: 0915486105 | PGS: N/A | List: 11.00 YOUR PRICE: 11.00 | ||||
| Beneficial and Toxic Effects of Aspirin | |||||||
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| Beneficial Effects: History, Uses, Labeling, and Poison Prevention Packaging (B. Bhooshan). Prostaglandins, Other Lipid Mediators, and the Mechanism of Action of Aspirin (A.K. Myers and P.W. Ramwell). Risk: Aspirin Toxicity (S.E. Feinman). Aspirin and Gastrointestinal Toxicity (S.E. Feinman). Aspirin Sensitivity in the Respiratory System (D.D. Stevenson). Aspirin-Related Urticaria and Angioedema (E.J. Bardana, Jr. and A. Montanaro). Benefit-Risk Assessment: The Role of Aspirin in Chemoprevention of Cancer and Its Effect on Mutagenicity (S.E. Feinman). Effects of Aspirin on Female Reproductive Function and on In Utero Development (I. Hertz-Picciotto). Biochemical Manifestations of Reye Syndrome: The Role of Aspirin (L.E. Kilpatrick). Aspirin and the Elderly: Therapeutic Implications (J. Karsh). Veterinary Use and Misuse (T.R.B. Barr). Summary and Conclusions. | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0849372976 | PGS: 144 | List: 289.95 YOUR PRICE: 275.45 | |||
| Bioadhesive Drug Delivery Systems | |||||||
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| Mucus Physiology and Pathology. Scaling Concepts and Molecular Theories of Adhesion of Synthetic Polymers to Glycoproteinic Networks. Test Methods of Bioadhesion. Bioadhesives/Mucoadhesives in Drug Delivery to the Gastrointestinal Tract. Nanoparticles as a Gastroadhesive Drug Delivery System. Mucoadhesive Buccal Patches for Peptide Delivery. Bioadhesive Dosage Forms for Buccal/Gingival Administration. Semisolid Dosage Forms as Buccal Bioadhesives. Bioadhesive Dosage Forms for Nasal Administration. Ocular Bioadhesive Delivery Systems. Nanoparticles as Bioadhesive Ocular Drug Delivery Systems. Bioadhesive Dosage Forms for Vaginal and Intrauterine Applications. | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 084935367X | PGS: 240 | List: 462.00 YOUR PRICE: 438.90 | |||
| Biochemical Targets of Plant Bioactive Compounds: A Pharmacological Reference Guide to Sites of Action and Biological Ef | |||||||
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| PLANT DEFENSIVE COMPOUNDS AND THEIR MOLECULAR TARGETS Introduction Organization and Scope of the Book Description of the Tables Using the Tables The Structural Diversity of Plant Defensive Compounds Plant Alkaloids Plant Phenolics Plant Terpenes Other Plant Compounds BIOCHEMISTRY - THE CHEMISTRY OF LIFE Introduction - Water-based Life Protein Structure Enzymes and Ligand-binding Proteins Metabolic Strategies Inhibition of Biochemical Processes by Plant Defensive Compounds NEUROTRANSMITTER- AND HORMONE-GATED ION CHANNELS Introduction - Electrical Signaling in Excitable Cells Ionotropic Neurotransmitter Receptors - Neurotransmitter-gated Ion Channels Structure and Function of Ionotropic Receptors ION PUMPS, LIGAND- AND VOLTAGE-GATED ION CHANNELS Introduction Ion Pumps Voltage-gated Na+ Channels Ligand-Regulated and Voltage-gated K+ Channels Voltage-gated Ca2+ Channels Ligand-gated Ca2+ Channels Chloride Transport and Voltage-regulated Chloride Channels PLASMA MEMBRANE G PROTEIN-COUPLED RECEPTORS Introduction - Signaling Via Heterotrimeric G Proteins G Protein-coupled Hormone and Neurotransmitter Receptors Hormones and Neurotransmitters Acting Via G Protein-coupled Receptors Activation of Specific G Protein-coupled Receptors Leucocyte- and Inflammation-related G Protein-linked Receptors Other G Protein-coupled Receptors NEUROTRANSMITTER TRANSPORTERS AND CONVERTERS Introduction Synthesis of Neurotransmitters Release of Neurotransmitters from Synaptic Vesicles Re-uptake of Neurotransmitters into Neurons and Synaptic Vesicles Neurotransmitter Degradation CYCLIC NUCLEOTIDE-, Ca2+- AND NITRIC OXIDE-BASED SIGNALING Introduction Ca2+- and Calmodulin-dependent Enzymes Adenylyl Cyclase Membrane-bound and Soluble Guanylyl Cyclases Nitric Oxide Synthesis Cyclic AMP- and Cyclic GMP-dependent Protein Kinases Protein Kinase Homologies and Phosphoprotein Phosphatases Cyclic Nucleotide Phosphodiesterases SIGNAL-REGULATED PROTEIN KINASES Introduction Cyclic AMP-dependent Protein Kinase Cyclic GMP-dependent Protein Kinase Protein Kinase C Ca2+ -calmodulin-dependent Protein Kinases AMP-dependent Protein Kinase Receptor Tyrosine Kinases Protein Kinase B Cytokine Activation of the JAK/STAT Pathway Cell Cycle Control Receptor Serine/Threonine Kinases Other Protein Kinases Phosphoprotein Phosphatases GENE EXPRESSION, CELL DIVISION AND APOPTOSIS Introduction Regulation of Gene Expression in Prokaryotes Regulation of Transcription in Eukaryotes RNA Processing and Translation Control of Translation Protein Processing and Post-translational Modification Protein Targeting Cell Division and Apoptosis HIV-1 Infection and HIV-1 Replication Plant Compounds Interfering with Gene Expression TASTE AND SMELL PERCEPTION, PHEROMONES AND SEMIOCHEMICALS Introduction Sweet Taste Receptors Bitter Taste Receptors Salty Taste Perception Sour Taste Perception Umami (Glutamate Taste Perception) Odorant Perception Animal Pheromones and Other Animal Bioactivities Produced by Plants Other Plant Semiochemicals Affecting Animal Behavior Odoriferous Animal Metabolites of Ingested Plant Compounds AGONISTS AND ANTAGONISTS OF CYTOSOLIC HORMONE RECEPTORS Introduction Steroid Hormones Non-steroid Cytosolic Hormone Receptor Ligands Plant Bioactives Affecting Cyctosolic Receptor-mediated Signaling POLYNUCLEOTIDES, POLYSACCHARIDES, PHOSPHOLIPIDS AND MEMBRANES Introduction Polynucleotides Polysaccharides and Oligosaccharides Phospholipids and Membranes INHIBITORS OF DIGESTION AND METABOLISM Introduction Glycohydrolases Proteases Glycolysis and Tricarboxylic Acid Cycle Mitochondrial Electron Transport and Oxidative Phosphorylation Gluconeogenesis Solute Translocation ANTI-INFLAMMATORY, ANTIOXIDANT AND ANTIDIABETIC PLANT COMPOUNDS Introduction Adhesion and Movement of Inflammatory Leucocytes Chemokines Phagocytosis Kinins, Cytokines, Platelet Activating Factor and Eicosanoids Plant-derived Anti-inflammatory Compounds Diabetes Mellitus and Plant Antidiabetic Compounds Summary Appendix Bibliography Compound Index Plant Genus Index Plant Common Names Index Subject Index Abbreviations | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0415308291 | PGS: N/A | List: 239.95 YOUR PRICE: 227.95 | |||
| Biochemistry and Function of Sterols | |||||||
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| Inhibitors of 2,3-Oxidosqualene Cyclase as Tools for Studying the Mechanism and Function of the Enzyme, L. Cattel and M. Ceruti Aromatase Inhibitors, J. O'Neal Johnston Variability of Metabolism and Function of Sterols in Insects, J.A. Svoboda Oxysterols and Apoptosis: Evidence for Gene Regulation Outside the Cholesterol Pathway, E.B. Thompson and S. Ayala-Torres Tracing Steroid Synthesis in Plants, H.W. Groeneveld Biochemistry and Molecular Biology of Sterol Synthesis in Saccharomyces cerevisiae, N.D. Lees, M. Bard, and D.R. Kirsch 19-Noraldosterone, Y. Takeda Enzymology of Phytosterol Transformations, W.D. Nes and M. Venkatramesh Isoprenoid Biosynthesis in Plants: Carbon Partitioning Within the Cytoplasmic Pathway, J.D. Newman and J. Chappell Mevalonate Biosynthesis in Plants, T.J. Bach, A. Boronat, N. Campos, A. Ferrer, and K.-U. Vollack Lanosterol Analogs: Dual-Action Inhibitors of Cholesterol Biosynthesis, L.L. Frye and D.A. Leonard Biochemistry and Function of Nematode Steroids, D.J. Chitwood Occurrence, Biosynthesis, and Putative Role of Ecdysteroids in Plants, J.H. Adler and R.J. Grebenok Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity by Side-Chain Oxysterols and Their Derivatives, E.J. Parish, S.C. Parish, and S. Li Biological Effects of Brassinosteroids, C. Brosa Vitamin D: A Hormonal Regulator of the cAMP Signaling Pathway, J.P. Berg and E. Haug Protein Isoprenylation in Plants, S.K. Randall and D.N. Crowell Chemical Modulation of Activity in Steroidal Estrogens, E. Palomino Use of Sterol Mutants as Probes for Sterol Functions in the Yeast, Saccharomyces cerevisiae, L.W. Parks, J.H. Crowley, F.W. Leak, S.J. Smith, and M.E. Tomeo Integration of the Metabolic Pathways of Steroids, Carotenoids, and Retinoids, A.M. Gawienowski Index | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0849376742 | PGS: 288 | List: 309.95 YOUR PRICE: 294.45 | |||
| Biodegradable Hydrogels for Drug Delivery | |||||||
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| Chapters, sub-chapters and selected sub-sections, some condensed for this space. All chapters end with a section of References. Introduction o Controlled Release Drug Delivery Systems o Hydrogels: Definition, Hydrogel as a Biomaterial, Biodegradable Hydrogels Biodegradation o Definitions: Bioresorption, Bioabsorption, Bioerosion, Biodeterioration o Mechanisms: Solubilization, Charge Formation Followed by Dissolution o Chemical Hydrolysis of Polymers:Enzyme-Catalyzed Hydrolysis o Biodegradable Hydrogels Types of Biodegradable Hydrogels o Hydrogels with Degradable Polymer Backbone: Crosslinked Hydrogels, Noncrosslinked Hydrogels o Hydrogels with Degradable Crosslinking Agents: Crosslinked with Small Molecules, Crosslinked with Oligopeptides, Crosslinked with Macromolecules o Hydrogels with Degradable Pendant Chains Chemical Gels o Polymerization in the Presence of Crosslinking Agents: Introduction of Double Bonds to Macromolecules, Determination of Double Bonds on the Macromonomers o Crosslinking of Water-Soluble Polymers: Crosslinking with Functional Groups, Nonspecific Crosslinking, Determination of the Degree of Crosslinking Physical Gels o Thermoreversible Gelling System: Gels with Thermomelting Properties,Gels with Thermogelation Properties o Thermoreversible Gelling Polysaccharides: Water-Soluble Polysaccharides, Gel-Forming Polysaccharides o Physical Gelation by Ion Complexation: Polymers with Hydroxyl Groups, Carrageenan, Gellan, Pectin, Alginate, Polyphosphazenes, Other Polyanions, Chitosan o Physical Gelation by Specific Interactions: Fibrin Gel, Mucus Gel, Actin Gel, Avidin-Biotin Mediated Gel, Antibody Mediated Gel, Lectin-Mediated Gel oDetermination of the Crosslink Density Chemically-Induced Degradation o Chemically-Induced Hydrolysis in the Body: Distribution and Elimination, Factors Influencing Chemically-Induced Hydrolysis o Chemically-Induced Hydrolysis of Polyesters: Poly(glycolic Acid), Poly(lactic Acid), Polycaprolactone, Poly(ethylene Terephthalate), Poly(ß-hydroxybutyrate), Polydioxanone o Polyester Hydrogels Enzyme-Catalyzed Degradation o Properties of Enzymes o Hydrolytic Enzymes in the Body: Gastrointestinal Tract, Reticuloendothelial System, Others o Factors Influencing Enzyme-Catalyzed Reactions: Conformation of Enzymes and Substrates, Presence of Polymer Molecules o Enzyme-Catalyzed Degradation of Modified Proteins: Albumin, Gelatin, Modified Enzymes o Enzyme-Catalyzed Degradation of Modified Polysaccharides: Dextran, Starch, Amylose, Chitosan, Chondroitin-6-Sulfate Biodegradable Drug Delivery Systems o Mechanisms of Drug Release: Diffusion-Controlled Systems, Swelling-Controlled Systems, Biodegradable Systems o Drug Release From Hydrogels with Biodegradable Backbones: Hydrogels Based on Protein/Polypeptides, Hydrogels Based on Polysaccharides, Biodegradable Hydrogels Based on Polyesters o Drug Release From Hydrogels with Degradable Crosslinking Agents: Hydrogels Crosslinked with Small Molecules, Hydrogels Crosslinked with Albumin o Drug Release from Hydrogels with Biodegradable Pendant Chains Future Development o Drug Loading o Drug Targeting o Drug Release o Degradation and Elimination o Use of Bioactive Polymers | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 1566760046 | PGS: 252 | List: 229.95 YOUR PRICE: 218.45 | |||
| Biologically Active Peptides: Design, Synthesis and Utilization | |||||||
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| Structural Approaches to Peptide Design: Computer Assisted Design - Bioactive Peptide Design Based on Antibody Structure - NMR Spectroscopy of Peptides and Proteins in Membrane Environments - Chemical Synthetic Aspects of Peptide Production: Large Scale Peptide Production - Chemically Modified Peptides - Biologically Active Peptides Mimics - Utilization of Bioactive Peptides: Synthetic Peptide-Based Vaccines and Antiviral Agents - MHC Binding Peptides - Extracellular Matrix Cell Attachment Peptides | |||||||
| CRC - TAYLOR & FRANCIS | S | ISBN: 0877629358 | PGS: 374 | List: 229.95 YOUR PRICE: 218.45 | |||
| Biology of Sleep Substances | |||||||
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| Candidate Substances, Research Background, and Biological Roles. Techniques for Isolation and Evaluation. Delta-Sleep-Inducing Peptide and Its Derivatives. Sleep-Promoting Substance (SPS) and Nucleosides. Muramyl Peptides and Immunoreactive Substances. Prostaglandins. Paradoxical Sleep (PS) Factors. Other Sleep Modulators. Interactions of Sleep Substances. Evolutionary Aspects. Index. | |||||||
| CRC - TAYLOR & FRANCIS | H | ISBN: 0849348226 | PGS: 216 | List: 359.95 YOUR PRICE: 341.95 | |||
| Biopharmaceutics and Clinical Pharmacokinetics, An Introduction, Fourth Edition, Revised and Expanded | |||||||
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| Introduction References Rates, Rate Constants, and Order Order Rates and Rate Constants Active and Passive Transport Introduction Passive Transport Active Transport References Pharmacokinetics Introduction Drug Disposition Constant-Rate Intravenous Infusion Compartmental Models and Their Limitations Absorption Rate Constants References Biopharmaceutics Extravascular Administration Absorption of Drugs from the Gastrointestinal Tract Factors Influencing Bioavailability Evaluation of the Bioavailability of a Single Drug Drug Delivery to Prolong Duration References Dosage Regimens Introduction Accumulation During Repetitive Dosing Adjustment of Dosage Regimen in Renal Failure Multiple Dosing of Constant-Rate Intravenous Infusions References Pharmacokinetic Aspects of Structural Modifications in Drug Design and Therapy Introduction Antimicrobial Agents Pharmacokinetics of Prodrugs Stereoisomers References Pharmacokinetic Applications in Clinical Practice Introduction Pharmacokinetic Drug Interactions Clinical Pharmacokinetics | |||||||
| MARCEL DEKKER - TAYLOR & FRANCIS & FRANC | H | ISBN: 0824775236 | PGS: 440 | List: 83.95 YOUR PRICE: 79.75 | |||
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